The application of ionizing radiation is an important part of modern medicine, research, and industry that enables the transfer of high technologies to daily practice. The risk associated with exposure to ionizing radiation has to be controlled and well balanced with achieved benefits. The central topic of our research activities is the assessment of radiation exposure in an accurate manner. Different experimental and computational methods for radiation dose and risk assessment are used to reduce the radiation burden for population, workers and patients, including dosimetry for early warning systems. Based on the fundamental radiation protection principles, services provided by our Laboratory include testing of radiation sources in medicine, industry and research, workplace monitoring and individual monitoring, radiation protection consultancy, patient dosimetry and shielding design. The ionizing radiation calibration laboratory is a Secondary Standards Dosimetry Laboratory that maintains national standards and disseminates the units of Gy and Sv. The Laboratory provides calibrations in terms of the Air Kerma, Absorbed Dose to water, Personal Dose Equivalent, Ambient Dose Equivalent in the fields of radiotherapy, diagnostic radiology and radiation protection. The Laboratory is a member of the WHO/IAEA network of SSDL and closely cooperates with the Directorate of Measures and Precious Metals (DMDM). Since 2014, it is a Designated Institute (DI) for ionizing radiation and part of the national metrology system.